Mdi and tdi dermal penetration studies

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Respiratory and other hazards of isocyanates. Skin as a route of exposure to protein allergens. Recent animal studies have documented that skin exposure to proteins such as ovalbumin or peanuts can induce systemic Th2-type sensitization and subsequent asthmatic responses Herrick et al. Assessing isocyanate exposures in polyurethane industry sectors using biological and air monitoring methods. Dermal and inhalation exposure to methylene bisphenyl isocyanate MDI in iron foundry workers. For example, NIOSH Health Hazard Evaluations of a variety of work settings have described workers with skin contact to isocyanates or uncured polyurethane products NIOSH , Quantification of isocyanate skin exposure is important for research, prevention, and control.
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Dermal uptake and excretion of 14C-toluene diisocyante (TDI) and 14C-methylene diphenyl diisocyanate (MDI) in male rats. Clinical signs and histopathology following dermal exposure of male rats to TDI

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Biological monitoring for isocyanates | Occupational Medicine | Oxford Academic

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Proceedings of the American Thoracic Society

Information on Registered Substances comes from registration dossiers which have been assigned a registration number. After washing of the exposed skin. The corresponding values for the dressing material were Skin as a route of exposure to protein allergens.
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